PHAGYO® Spray
(Pyo Bacteriophagum)
International non-patented name: Pyo Bacteriophagum spray.
Description: Various intensity yellow, transparent solution with specific taste.
Composition:
Acitve ingredients:
Phagolysates sterile filtration mixture of bacterias: Streptococcus, Staphylococcus, E.Coli, Pseudomonas aeruginosa, Proteus.
Qantitative composition: 1 ml of the product contains Specific phages:
Bacteriophagum Streptococcus,
Bacteriophagum Staphylococcus,
Bacteriophagum E.Coli,
Bacteriophagum Pseudomonas aeruginosa,
Bacteriophagum Proteus,
in not less than 105 each one.
Pharmaceutical form: Spray, 20 ml sterile solution for local and external use.
Pharmakotherapeutic group: Specific antibacterial medication.
ATC code: J01XX.
Pharmacological action: Bacteriophage is a specific virus of bacteria which is adsorbed on the membrane of cell of homological bacteria, destroying its integrity penetrates into cell, propagates itself and causes its lysis.
Phagyo spray contains only selected virulent phages of bacterais (Streptococcus, Staphylococcus, E.Coli, Pseudomonas aeruginosa, Proteus) conditioning high activity and effectiveness of the preparation.
Despite of the way of administration preparations of Bacteriophage are rapidly penetrated in blood and lympha and thus easily reach to the disease. It is secreted mainly in kidneys and in gastrointestinal tract.
Therapeutical indications: Phagyo spray is used for treatment and prophylaxis of the purulent diseases caused by bacterias Streptococcus, Staphylococcus, E.Coli, Pseudomonas aeruginosa, Proteus in patients of all age and high risk groups.
The medication is used for:
the treatement of pharyngitis, laryngitis and tonsilitis, for treatement and prevention of inflamation of oral cavity such as glositis, gingivitis, stomatitis. For treatement of purulent wounds, burns, abscesis, plegmoni, furuncles, carbuncles.
For the treatment of inflamation diseases in infants (omphalitis, pyodermia) .
In other diseases caused by the bactera: Streptococcus, Staphylococcus, E.Coli, Pseudomonas aeruginosa, Proteus.
The medication is used for prevention of the following diseases: After different manipulations in oral cavity, surgical interventions (periodontal procedures, tooth extraction , etc.).
For processing of fresh wounds in stationery as well as houshold conditions; For prevention of inflamation complications in surgical manipulations and intervetion. For prevention of inflamation in severe respiratory-viral infectious diseases.
Contraindications: Increased sensitivity to any components of the vial content of the product.
Special precautions:
No special precautionary measures are indicated for preparation use.
Shake the vial before usage. Content must be transparent and without sediment.
Do not administer turbid preparation!
After usage, the vial with liquid should be stored in a refrigerator.
Do not freeze the product!
After opening the vial (first spray) the preparation can be stored for 20 days at 2°C-8°C.
The preparation can be swallowed during oral cavity treatment.
Interaction with other pharmaceutical products: Incompatibility of the preparation with other pharmaceutical products is not ascertained. The preparation is possible to be used in complex treatment with other pharmaceutical products, including antibacterial preparations (antibiotics).
Pregnancy and lactation: The product is allowed to be used in pregnancy and lactation.
Driving and machinery operations: Using of the preparation doesn’t influence on ability of driving and machinery operations.
Keep out of reach of children.
Dosage, rule and way of administration: One of the important premises of phagotherapy effectiveness is the definition of sensitivity of microorganism to phage (to phages included in the preparation) defiant the disease. The preparation is more effective while using in early stage of the disease.
Phagyo spray should be prescribed by physician.
When the product is used orally (oral cavity and pharynx) it might be administered 30 minutes prior to meal or after for more therapeutic effect.
In children below 6 years old – 5 sprays in 2-3 hours intervals for 4-5 times per day.
From 6 to 12 years old children – 8 sprays in 2-4 hours intervals, for 4-5 times per day.
In adults and elderly patients – 8-10 sprays in 2-4 hours intervals for 4-5 times per day.
The treatment should be prolonged for 5-10 days.
In case of external administration the dosage (quantity of sprays) of the product should be determined by physician considering the size of the affected area.
Remark: In case if chemical antiseptic products have been used before treatment for oral cavity processing, this product should be used after 3 hours or the proper areas should be processed with sterile 0,9% physiological solution.
Over dosage: There is no any information about over dosage of the preparation of Bacteriophage.
Adverse reactions: The preparation is nontoxic. There is no data evident about any side effects or harming influence on human body after administration of the product.
Form and package of the product:
20ml glass vial containing solution is closed by impermeable mechanical sprayer with transparent cap. One 10ml vial is represented in a cardboard package with instruction leaflet.
Keeping and transportation terms: Keep in a dry place away from light at 2°C – 25°C temperature.
Transportation of the product is allowed to be accomplished by any closed transport providing stabile temperature regime for whole transportation period.
Expiration date: The product is valid for 2 years since the date of manufacture in case if storage terms are completely protected.
The product shouldn’t be used after the date of expiration.
Release from drug stores: Released without prescription.
Manufacturer: JSC “Biochimpharm”
